(10月28日)Bio-inspired Molecular Design and Functionalization of Supramolecular Architectures
日期:2024-10-23 阅读次数: 作者: 来源:

报  告  人: 盐谷光彦(Mitsuhiko SHIONOYA)

报告时间: 2024-10-28上午10:00~上午11:00

报告地点: 嘉锡楼413

 


 

 

报告人简介:

盐谷光彦(Mitsuhiko SHIONOYA)教授于1986年在日本东京大学获得药学博士学位,1986-1999年分别在日本广岛大学、国立分子科学研究所、综合研究大学院大学任助理教授、副教授、教授,1999-2024年任日本东京大学化学系教授,2024至今任东京理科大学教授,东京大学荣誉教授。

盐谷光彦教授研究组致力于仿生精密合成和超分子金属配合物的功能创造,包括:(1)金属阵列:以仿生人工分子、合成分子、单原子为模板;(2)纳米空间:有机和配位胶囊和笼中的分子识别和反应;(3)分子运动:通过超分子齿轮进行旋转和切换;(4)配位不对称:手性金属配合物与不对称反应;(5)以元素为中心的金属离子簇:设计与合成、光学生物成像、催化。盐谷光彦教授是金属配体材料设计研究领域的著名学者,在学术上取得了诸多荣誉,其中包括:伊扎特-克里斯滕森国际奖(2020年)、池原奖(日本核酸化学学会,2023年)、日本化学学会奖(2020年)、日本配位化学学会奖(2018年)、日本文部科学大臣表彰-科学技术奖(2016年)等。盐谷光彦教授已发表了280多篇的研究论文,发表在ScienceNat. Chem.Nat. Nanotechnol.Chem. Soc. Rev.Nat. Commun.、J. Am. Chem. Soc.Angew. Chem.等顶级期刊上,其研究成果被引用12000余次,h-index为63;曾担任Acc. Chem. Res.编委,日本科学委员会委员,日本化学会代表理事、首席副会长,2013年至今担任Chemistry Letters主编,2001年至今担任Supramol. Chem.编委。

 

 

Mitsuhiko SHIONOYA

Professor, Tokyo University of Science

Emeritus Professor, The University of Tokyo

Tel: +81-4-7122-9645, E-mail: shionoya@rs.tus.ac.jp

Educational and Professional Experience

1982-1986 The University of Tokyo (Pharmaceutical Sciences)

1986-1988 Assistant Professor, Hiroshima University

1988-1990 Assistant Professor, Institute for Molecular Science

1990-1991 Assistant Professor, Hiroshima University

1991-1994 Lecturer, Hiroshima University

1991 Visiting Researcher, University of Texas at Austin, USA

1994-1995 Associate Professor, Hiroshima University

1995-1999 Professor, Institute for Molecular Science

1995-1999 Professor, The Graduate University for Advanced Studies

1999-2024 Professor, The University of Tokyo (Department of Chemistry)

2024-present Professor, Tokyo University of Science

Awards

2003 Visiting Professor, University of Louis Pasteur

2007 Visiting Professor, Ludwig-Maximilians-Universität Munich

2007 Inoue Prize for Science

2007 The Chemical Society of Japan Award for Creative Work

2008 University of Louis Pasteur Medal

2014 Visiting Professor, University of Strasbourg

2016 Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology

2018 Japan Society of Coordination Chemistry Award

2020 Chemistry Society of Japan Award

2020 International Izatt-Christensen Award

2023 Ikehara Award 2023 (Japan Society of Nucleic Acids Chemistry)

Social Activities

Editorial Board of Supramol. Chem. (2001–present)

The Chemistry Society of Japan, Associate & Senior Editors of Bull. Chem. Soc. Jpn. (2002–2008)

ULP-UT International Exchange Program Coordinator (2004–2009)

UDS-UT International Exchange Program Coordinator (2009–2023)

International Organizing Committee Member of ISMSC, Japan Representative (2012–2019)

The Chemistry Society of Japan, Director (2012–2014)

Senior Program Officer, JSPS / Research Center for Science Systems (2012–2015)

Editor-in-Chief, Chemistry Letters (2013–present)

Science Council of Japan, Member (2014–2020)

Editorial Board Member of Acc. Chem. Res. (2014–2020)

Representative Director, (First) Vice President, The Chemical Society of Japan (2021–2023)

Research Interests and Subjects

Bio-Inorganic Chemistry, Supramolecular Chemistry, Coordination Chemistry, Organometallic Chemistry

Bio-inspired precision synthesis and functional creation of supramolecular metal complexes

(1) Metal array: using bioinspired artificial molecules, synthetic molecules, and single atoms as templates

(2) Nano space: molecular recognition and reactions in organic and coordination capsules and cages

(3) Molecular motion: engaged rotation and switching by supramolecular gears

(4) Coordination asymmetry: chiral-at-metal complexes and asymmetric reactions

(5) Element-centered metal ion clusters: design and synthesis, optical bioimaging, catalysis

 

 

 

报告摘要:

Supermolecules, in which a certain number of organic components and metal ions self-assemble through directional dynamic bond formation, provide elaborate molecular systems that can express unique functions in array, space, motion, and asymmetry. In the design of supramolecular metal complexes, the most important factors are the type of molecules and ions that make up the complex, the surface properties that enables the interactions, and the chemical environment. In this lecture, I will focus on supramolecular metal complexes such as artificial metal-DNAs,1,2,8 metal-macrocycle frameworks,3.7 molecular rotors,4.9 asymmetric induction of metal-centered chirality,5 and C-centered metal ion clusters for bioimaging,6,10 which were developed by extracting the essence of the structure and function of biomolecules.

References

1 Tanaka K., Tengeiji A., Kato T., Toyama N., Shionoya M., Science 299, 1212–1213 (2003).

2 Tanaka K., Clever G., Takezawa Y., Yanada Y., Kaul C., Shionoya M., Carell T., Nat. Nanotechnol. 1, 190–194 (2006).

3 Kubota R., Tashiro S., Shiro M., Shionoya M., Nat. Chem. 6, 913–918 (2014).

4 Ube H., Yamada Y., Sato H., Shionoya M., Nat. Commun. 8, 14296 (2017).

5 Endo K., Liu Y., Ube H., Nagata K., Shionoya M., Nat. Commun. 11, 6263 (2020).

6 Lei Z., Endo M., Ube H., Shiraogawa T., Zhao P., Nagata K., Pei X., Eguchi T., Kamachi T., Ehara M., Ozawa T., Shionoya M., Nat. Commun. 13, 4288 (2022).

7 R. Hayashi, S. Tashiro, M. Asakura, S. Mitsui, M. Shionoya, Nat. Commun. 14, 4490 (2023).

8 Y. Takezawa, K. Mori, W.-E. Huang, K. Nishiyama, T. Xing, T. Nakama, M. Shionoya, Nat. Commun. 14, 4759 (2023).

9 T. Nakajima, S. Tashiro, M. Shionoya, Nat. Commun. 14, 7868 (2023).

10 X.-L. Pei, P. Zhao, H. Ube, Z. Lei, M. Ehara, M. Shionoya, Nat. Commun. 15, 5024 (2024).