吴韶华

职 称: 教授

学 历: 博士研究生

电子邮件: wsh@fzu.edu.cn

研究方向: 1. 生物(光)电分析化学 2. 表面增强拉曼光谱生物传感

教育工作经历 (Education and working experiences)

现为福州大学化学学院,教授、博导

2015-2016美国华盛顿州立大学,访问学者

1997.8至今福州大学化学学院,教师

福州大学分析化学专业,理学博士

福建师范大学高分子化学与物理专业,理学硕士

福建师范大学化学教育专业,理学学士

科研简介 (Scientific research)

主要从事生物(光)电分析化学、表面增强拉曼光谱生物传感等方向的研究。目前以第一作者或通讯作者在ACS Sensors, Biosensors and Bioelectronic,Sensors and Actuators B: Chemical, Analytica Chimica Acta,等刊物上发表SCI论文20余篇。主持国家自然科学基金2项,福建省自然科学基金2项等。

科研项目 (Scientific research projects)

国家自然科学基金面上项目(21575026, 2016-2019)

国家自然科学基金青年项目(21105013, 2012-2014)

福建省自然科学基金面上项目(2022J01536, 2022-2025)

福建省自然科学基金自由探索项目(2006J0258, 2006-2008)

陈可冀中西医结合发展基金(CKJ2007031ZYX200709,2007-2009)

福州大学科技发展基金

福州大学科研启动基金

获奖情况 (awards & honors)

2022福州大学优秀硕士毕业论文指导教师奖

2022福州大学“杨鸿耀奖教金”

2021福州大学教学优秀奖二等奖

2021第四届福州大学“福能奖教金”

2021福州大学优秀硕士毕业论文指导教师奖

2021福州大学优秀本科毕业论文指导教师奖

2018福州大学本科教学成果奖二等奖(排名第二)

2018福州大学教学优秀奖二等奖

2018国家优秀研究生奖学金(指导教师)

2017福州大学“杨鸿耀奖教金”

2017福州大学本科教学成果奖一等奖(排名第四)

2016第十届全国大学生化学实验邀请赛二等奖(指导教师)

2015国家优秀研究生奖学金(指导教师)

代表性论文 (Representative papers)

1.Lei-Xin Jin, Qi-Meng Wang, Shu-Jiao Zhu, Cai-Lian Zhu, Jian-Jun Sun,Shao-Hua Wu*, Gold nanocube-enhanced SERS biosensor based on heated electrode coupled with exonuclease III-assisted cycle amplification for sensitive detection of flap endonuclease 1 activity,Talanta,2025, 286,127500.

2.Zhen-Zhen Mi, Hao-Cheng Hu, Jian-Jun Sun,Shao-Hua Wu*,Heating promoted super sensitive electrochemical detection of p53 gene based on alkaline phosphatase and nicking endonuclease Nt.BstNBI-assisted target recycling amplification strategy at heated gold disk electrode,Analytica Chimica Acta, 2023, 1275, 341583.

3.Yu-Yang Wei,Shao-Hua Wu*, Qi-Meng Wang, Jian-Jun Sun,A novel split-type photoelectrochemical biosensor based on double-strand specific nuclease-assisted cycle amplification coupled with plasmonic Ag enhanced BiVO4performance for sensitive detection of microRNA-155,Sensors & Actuators: B. Chemical,2022,369,132251.

4.Hao-Cheng Hu,Shao-Hua Wu*,Lei-Xin Jin,Jian-Jun Sun,Plasmonic Au nanocube enhanced SERS biosensor based on heated electrode and strand displacement amplification for highly sensitive detection of Dam methyltransferase activity,Biosensors and Bioelectronics, 2022, 210, 114283.

5.Yan Liu,Shao-Hua Wu*, Xing-Yuan Du, and Jian-Jun Sun,Plasmonic Ag Nanocube Enhanced SERS Biosensor for Sensitive Detection of Oral Cancer DNA Based on Nicking Endonuclease Signal Amplification and Heated Electrode,Sensors and Actuators B: Chemical, 2021, 338,129854.

6.Xing-Yuan Du,Shao-Hua Wu*, Xiao-Bin Huang, and Jian-Jun Sun,Ag Nanocubes Coupled with Heating-Enhanced DSN-Assisted Cycling Amplification for Surface-Enhanced Raman Spectroscopy Detection of MicroRNA-21,ACS Appl. Nano Mater., 2021, 4(3),2565-2574.

7.Xiao-Bin Huang,Shao-Hua Wu*, Hao-Cheng-Hu, Jian-Jun Sun,AuNanostar@4-MBA@Au Core–Shell Nanostructure Coupled with Exonuclease III-Assisted Cycling Amplification for Ultrasensitive SERS Detection of Ochratoxin A,ACS Sensors, 2020, 5, 2636-2643.

8.Shao-Hua Wu*, Xiao-Bin Huang, You Tang, Li-Min Ma, Yan Liu, Jian-Jun Sun, Temperature controllable electrochemical sensors based on horseradish peroxidase as electrocatalyst at heated Au disk electrode and its preliminary application for H2O2detection,Analytica Chimica Acta, 2020, 1096, 44-52.

9.Sen Yang, Xing Chen, Zhen-Zhen Mi, Zhi-Min Chen, Xiao-Dong Li, Jian-Jun Sun*,Shao-Hua Wu*,Temperaturecontrollable electrodes with a one-parameter calibration, ACS Sensors, 2019, 4, 1594−1602.

10.Shao-Hua Wu*, Biao Zhang, Fang-Fang Wang, Zhen-Zhen Mi, Jian-Jun Sun*,Heating enhanced sensitive and selective electrochemical detection of Hg2+based on T-Hg2+-T structure and exonuclease III-assisted target recycling amplification strategy at heated gold disk electrode,Biosensors and Bioelectronic, 2018, 104, 145–151.

11.Shao-Hua Wu, Yi-Fan Zeng, Liang Chen, You Tang, Qiong-Lin Xu, Jian-Jun Sun*,Amplified electrochemical DNA sensor based on Hemin/G-quadruplex DNAzyme as electrocatalyst at gold particles modified heated gold disk electrode,Sensors and Actuators B: Chemical, 2016, 225, 228-232.

12.Shao-Hua Wu, You Tang, Liang Chen, Xian-Gui Ma, Song-Mao Tian, Jian-Jun Sun*,Amplified electrochemical hydrogen peroxide reduction based on hemin/G-quadruplex DNAzyme as electrocatalyst at gold particles modified heated copper disk electrode,Biosensors and Bioelectronics, 2015, 73, 41-46.

13.Shao-Hua Wu, Zhao-Yan Zheng, Ji-Fang Zhang, Zi-Wang Song, Lei Fang and Jian-Jun Sun*,Sub-ppt Level Detection of Mercury(II) Based on Anodic Stripping Voltammetry with Prestripping Step at an In Situ Formed Bismuth Film Modified Glassy Carbon Electrode,Elctroanalysis, 2015, 27, 1610-1615.

14.Shao-Hua Wu, Bao-Jian Zhu, Zong-Xiong Huang, Jian-Jun Sun*, A heated pencil lead disk electrode with direct current and its preliminary application for highly sensitive detection of luteolin,Electrochemistry Communications, 2013, 28, 47-50.

15.Shao-Hua Wu, Bao-Jian Zhu, Zong-Xiong Huang, Jian-Jun Sun*,A new heated nickel oxyhydroxide covered nickel wire electrode and its improved electrocatalytic oxidation for methanol,Electroanalysis, 2012, 24 (5), 1095–1099.

16.Shao-Hua Wu, Fa-Hui Nie, Qi-Zhen Chen and Jian-Jun Sun*, Highly sensitive detection of silybin based on adsorptive stripping analysis at single-sided heated screen-printed carbon electrodes modified with multi-walled carbon nanotubes with direct current heating,Analytica Chimica Acta, 2011, 687, 43-49.

17.Shao-Hua Wu, Fa-Hui Nie, Qi-Zhen Chen and Jian-Jun Sun*, Electrocatalytic oxidation and nanomolar detection of hydrazine by luteolin electrodeposited at a multi-walled carbon nanotube and ionic liquid composite modified screen printed carbon electrode,Analytical Methods, 2010, 2, 1729–1736

18.Shao-Hua Wu, Jian-Jun Sun*, De-Feng Zhang, Zhi-Bin Lin,Fa-Hui Nie, He-Yuan Qiu, Guo-Nan Chen,Nanomolar detection of rutin based on adsorptive stripping analysis at single-sided heated graphite cylindrical electrodes with direct current heating,Electrochimica Acta, 2008 ,53(22), 6596–6601.

19.Shao-Hua Wu, Jian-Jun Sun*,Zhi-Bin Lin, Ai-Hong Wu, Yong-Ming Zeng, Liang Guo, De-Feng Zhang, Hui-Ming Dai, Guo-Nan Chen,Adsorptive Stripping Analysis of Riboflavin at Electrically Heated Graphite Cylindrical Electrodes, Electroanalysis, 2007, 19(21),2251-2257.

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