姚宇航

职 称: 副教授

学 历: 博士研究生

电子邮件: yuhangyao@fzu.edu.cn

研究方向: 1. 小分子荧光探针。 2. 生物正交催化。 3. 人工金属酶。 4. PROTAC。 5. 多肽自组装。

教育工作经历 (Education and working experiences)

2023-至今福州大学,化学学院,副教授。

2020-2023北京大学,化学与分子工程学院,博士后(合作导师:高松教授、张俊龙教授)。

2015-2020,北京大学,化学与分子工程学院,无机化学,理学博士(导师:张俊龙教授)。

2011-2015,大连理工大学,化工与环境生命学部,应用化学,理学学士。

科研简介 (Scientific research)

主要从事小分子荧光探针、生物正交催化等化学生物学研究。目前以第一作者(含共一)及通讯作者在J. Am. Chem. Soc.,Chem. Sci.等刊物上发表SCI论文13篇。主持国家自然科学青年基金1项。

科研项目 (Scientific research projects)

国家自然科学基金青年项目(22404025, 2025-2027);

福州大学科研启动基金

获奖情况 (awards & honors)

2020年,北京大学博雅博士后

2022年,北京分子科学国家研究中心BMS Junior Fellow

2023年,福建省C类高层次人才

代表性论文 (Representative papers)

1.Yuheng Guo, Fang Jiang, Xiaohui Zhu, Wen He, Sijie Song, Xuecen Shou, Mengnan Wu, Ting Wu, Tingjing Huang, Zhi Ye, Xuyang Wang, Zhitong Chen, Yu He,Yuhang Yao*, Zhaowei Chen*, Huanghao Yang*, An enzyme-gated bioorthogonal catalytic nanoreactor for tumor-specific prodrug activation,Nano Res.,2025, 18, 94907134.

2.Yuhang Yao,Jia-Hui Wu,Guiyu Liu,Ruijing Zhang, Zi-Shu Yang, Song Gao, Tai-Chu Lau* and Jun-Long Zhang*, A Bio-Inspired Bimetallic Fe-M Catalyst for Electro- and Photochemical CO2Reduction,ChemCatChem,2024, e202301705.

3.Yuhang Yao,Jiyun Hu,Guiyu Liu,Yin-Shan Meng, Song Gao and Jun-Long Zhang*, Fluoride counterion boosts gold(I) catalysis: case studies for hydrodefluorination and CO2hydrosilylation,Inorg. Chem. Front.,2023,10, 5573-5583. (Cover).

4.Yuhang Yao,Guangliu Ran,Chun-Liang Hou,Ruijing Zhang, Daniel N. Mangel, Zi-Shu Yang, Mengliang Zhu, Wenkai Zhang,* Jing Zhang,* Jonathan L. Sessler,* Song Gao and Jun-Long Zhang*, Nonaromatic organonickel(II) phototheranostics,J. Am. Chem. Soc.,2022,144, 7346-7356.

5.Yuhang Yao, Jun-Long Zhang*, Porpholactone chemistry: regioisomeric effect of β-substituents and biological applications of rare earth complexes,J. Chin. Rare. Earth. Soc.,2021,39, 456-468.

6.Yuhang Yao, Chun-Liang Hou, Zi-Shu Yang, Guangliu Ran, Lei Kang, Cuicui Li, Wenkai Zhang,* Jing Zhang* and Jun-Long Zhang*, Unusual near infrared (NIR) fluorescent palladium(II) macrocyclic complexes containing M–C bonds with bioimaging capability,Chem. Sci.,2019,10, 10170-10178.

7.Yuhang Yao, Hao-Yan Yin, Yingying Ning, Jian Wang, Yin-Shan Meng, Xinyue Huang, Wenkai Zhang, Lei Kang, and Jun-Long Zhang*, Strong fluorescent lanthanide salen complexes: photophysical properties, excited-state dynamics, and bioimaging,Inorg. Chem.,2019,58, 1806-1814 (Cover).

8.Yuhang Yao,Yu Rao,Yiwei Liu, Liang Jiang, Jin Xiong, Ying-Jie Fan, Zhen Shen,* Jonathan L. Sessler* and Jun-Long Zhang*, Aromaticity versus regioisomeric effect of β-substituents in porphyrinoids,Phys. Chem. Chem. Phys.,2019,21, 10152-10162.

9.Yuhang Yao, Xuedan Song, Jieshan Qiu, Ce Hao*, Interaction between formaldehyde and luminescent MOFs [Zn(NH2bdc)(bix)]nin the electronic excited state,J. Phys. Chem. A,2014,158, 143-151.

10.Chun-Liang Hou,Yuhang Yao,Da Wang, Jing Zhang,* Jun-Long Zhang*, Orthogonally arranged tripyrrin–BODIPY conjugates with an “edge to plane” mode,Org. Chem. Front.,2019,6, 2266–2274.

11.Jun-Fei Wang,Yuhang Yao,Yingying Ning, Yin-Shan Meng, Chun-Liang Hou, Jing Zhang* and Jun-Long Zhang*, The design of rigid cyclic tripyrrins: the importance of intermolecular interactions on aggregation and luminescence,Org. Chem. Front.,2018,5, 1877–1885 (Cover).

12.Hang Zhang,Wen-Chuan Xie,Yuhang Yao,Zi-Yi Tang, Wen-Xiu Ni, BingWu Wang, Song Gao, Jonathan L. Sessler* and Jun-Long Zhang*, Electrostatic Force-Enabled Microneedle Patches that Exploit Photoredox Catalysis for Transdermal Phototherapy,ACS Appl. Mater. Interfaces,2024, DOI: 10.1021/acsami.4c18211.

Mengliang Zhu,Hang Zhang,Yuhang Yao,Mingpu Wen, Guangliu Ran, Yi Yu, Ruijing Zhang, Xing-Jie Liang, Jing Zhang, Wenkai Zhang* and Jun-Long Zhang*, More is different: progressive β-thiolation induced-porphyrin aggregation switches singlet oxygen photosensitization,Chem. Sci.,2024,15, 13841–13852.

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