姓    名：	吴韶华
	性    别：	女
	职    称：	教授
	学    历：	博士
	职    务：
	电    话：
	专    业：	分析化学
	电子邮件：	wsh@fzu.edu.cn
	研究方向：	生物电分析化学 表面增强拉曼光谱生物传感

教育工作经历

本科：福建师范大学化学系

硕士：福建师范大学高分子研究所

博士：福州大学化学学院

2015.3-2016.3美国华盛顿州立大学访学

       1997.8 至今福州大学化学学院教师

 

教学简介

本科生课程：《有机化学B》、《有机化学实验J上》、《有机化学实验J下》《综合化学实验一》

        研究生课程：《高等分析化学实验》

科研简介

 

主要从事分析化学方向的研究工作。主要的研究方向有（1）生物电分析化学；（2）表面增强拉曼光谱生物传感。在重要学术期刊《Biosensors and Bioelectronic》, 《ACS Sensors》,《Sensors and Actuators B: Chemical》，《Electrochemistry Communications》，《Analytica Chimica Acta》,《Electrochimica Acta》, 《Electroanalysis》等已发表SCI论文十多篇，主持多项自然科学基金项目。

 
 

社会兼职

科研项目

主持的科研项目：

7.基于热控电极和工具酶的电化学DNA传感器研究(2022J01536)，福建省自然科学基金，2022.8-2025.8

6.基于直流加热热控电极的电化学表面增强拉曼光谱联用及其分析应用研究(21575026), 国家自然科学基金面上项目，2016.01-2019.12

5.基于直流加热热控电极的功能性核酸生物电化学传感器及其分析应用研究(21105013)，国家自然科学基金青年项目，2012.1-2014.12

4.基于热控电极的电化学免疫传感器研究(022398)，福州大学科研基金，2011.6-2014.8

3.热电极应用于核黄素衍生物电化学行为研究及分析检测(2006J0258)，福建省自然科学基金， 2006.5-2008.12

2.黄素类化合物在热电极上的电化学行为研究及分析检测(2006-XY-06)，福州大学科技发展基金，2006.5-2008.12

1.黄酮类化合物在热电极上的电化学行为研究及分析检测(CKJ2007031ZYX200709)，陈可冀中西医结合发展基金，2007.9 -2009.9

 

代表性论文

第一作者或通讯作者论文：

18.Heating promoted super sensitive electrochemical detection of p53 gene based on alkaline phosphatase and nicking endonuclease Nt.BstNBI-assisted target recycling amplification strategy at heated gold disk electrode, Zhen-Zhen Mi, Hao-Cheng Hu, Jian-Jun Sun, Shao-Hua Wu*, Analytica Chimica Acta 1275 (2023) 341583

17.A novel split-type photoelectrochemical biosensor based on double-strand specific nuclease-assisted cycle amplification coupled with plasmonic Ag enhanced BiVO4 performance for sensitive detection of microRNA-155，Yu-Yang Wei, Shao-Hua Wu*, Qi-Meng Wang, Jian-Jun Sun，Sensors & Actuators: B. Chemical 369 (2022) 132251

16. Plasmonic Au nanocube enhanced SERS biosensor based on heated electrode and strand displacement amplification for highly sensitive detection of Dam methyltransferase activity，Hao-Cheng Hu，Shao-Hua Wu*，Lei-Xin Jin，Jian-Jun Sun，Biosensors and Bioelectronics, 210, (2022) 114283

15. Plasmonic Ag Nanocube Enhanced SERS Biosensor for Sensitive Detection of Oral Cancer DNA Based on Nicking Endonuclease Signal Amplification and Heated Electrode, Yan Liu, Shao-Hua Wu*, Xing-Yuan Du, and Jian-Jun Sun, Sensors and Actuators B: Chemical, 338 (2021) 129854.

14. Ag Nanocubes Coupled with Heating-Enhanced DSN-Assisted Cycling Amplification for Surface-Enhanced Raman Spectroscopy Detection of MicroRNA-21, Xing-Yuan Du, Shao-Hua Wu*, Xiao-Bin Huang, and Jian-Jun Sun, ACS Appl. Nano Mater., 2021, 4（3）,2565-2574.

13. AuNanostar@4-MBA@Au Core–Shell Nanostructure Coupled with Exonuclease III-Assisted Cycling Amplification for Ultrasensitive SERS Detection of Ochratoxin A, Xiao-Bin Huang, Shao-Hua Wu*, Hao-Cheng-Hu, Jian-Jun Sun, ACS Sensors, 2020, 5, 2636-2643.

12. Temperature controllable electrochemical sensors based on horseradish peroxidase as electrocatalyst at heated Au disk electrode and its preliminary application for H₂O₂ detection, Shao-Hua Wu*, Xiao-Bin Huang, You Tang, Li-Min Ma, Yan Liu, Jian-Jun Sun, Analytica Chimica Acta, 2020, 1096, 44-52

11. Temperature-controllable electrodes with a one-parameter calibration, Sen Yang, Xing Chen, Zhen-Zhen Mi, Zhi-Min Chen, Xiao-Dong Li, Jian-Jun Sun*, Shao-Hua Wu*, ACS Sensors, 2019, 4, 1594−1602

10. Heating enhanced sensitive and selective electrochemical detection of Hg²⁺ based on T-Hg²⁺-T structure and exonuclease III-assisted target recycling amplification strategy at heated gold disk electrode, Shao-Hua Wu*, Biao Zhang, Fang-Fang Wang, Zhen-Zhen Mi, Jian-Jun Sun*, Biosensors and Bioelectronic, 2018, 104, 145–151.

9.Amplified electrochemical DNA sensor based on Hemin/G-quadruplex DNAzyme as electrocatalyst at gold particles modified heated gold disk electrode, Shao-Hua Wu, Yi-Fan Zeng, Liang Chen, You Tang, Qiong-Lin Xu, Jian-Jun Sun*, Sensors and Actuators B: Chemical, 2016, 225, 228-232.

8.Amplified electrochemical hydrogen peroxide reduction based on hemin/G-quadruplex DNAzyme as electrocatalyst at gold particles modified heated copper disk electrode, Shao-Hua Wu, You Tang, Liang Chen, Xian-Gui Ma, Song-Mao Tian, Jian-Jun Sun*, Biosensors and Bioelectronics, 2015, 73, 41-46.

7.Sub-ppt Level Detection of Mercury(II) Based on Anodic Stripping Voltammetry with Prestripping Step at an In Situ Formed Bismuth Film Modified Glassy Carbon Electrode, Shao-Hua Wu, Zhao-Yan Zheng, Ji-Fang Zhang, Zi-Wang Song, Lei Fang and Jian-Jun Sun*, Elctroanalysis, 2015, 27 (7), 1610-1615.

6. A heated pencil lead disk electrode with direct current and its preliminary application for highly sensitive detection of luteolin, Shao-Hua Wu, Bao-Jian Zhu, Zong-Xiong Huang, Jian-Jun Sun*, Electrochemistry Communications, 2013, 28, 47-50.

5. A new heated nickel oxyhydroxide covered nickel wire electrode and its improved electrocatalytic oxidation for methanol, Shao-Hua Wu, Bao-Jian Zhu, Zong-Xiong Huang, Jian-Jun Sun*, Electroanalysis, 2012, 24 (5), 1095–1099.

4. Highly sensitive detection of silybin based on adsorptive stripping analysis at single-sided heated screen-printed carbon electrodes modified with multi-walled carbon nanotubes with direct current heating, Shao-Hua Wu, Fa-Hui Nie, Qi-Zhen Chen and Jian-Jun Sun*, Analytica Chimica Acta, 2011, 687, 43-49.

3. Electrocatalytic oxidation and nanomolar detection of hydrazine by luteolin electrodeposited at a multi-walled carbon nanotube and ionic liquid composite modified screen printed carbon electrode, Shao-Hua Wu, Fa-Hui Nie, Qi-Zhen Chen and Jian-Jun Sun*, Analytical Methods, 2010, 2, 1729–1736

2. Nanomolar detection of rutin based on adsorptive stripping analysis at single-sided heated graphite cylindrical electrodes with direct current heating, Shao-Hua Wu, Jian-Jun Sun*, De-Feng Zhang, Zhi-Bin Lin,Fa-Hui Nie, He-Yuan Qiu, Guo-Nan Chen, Electrochimica Acta, 2008 ,53(22),  6596–6601.

1.Adsorptive Stripping Analysis of Riboflavin at Electrically Heated Graphite Cylindrical Electrodes, Shao-Hua Wu, Jian-Jun Sun,* Zhi-Bin Lin, Ai-Hong Wu, Yong-Ming Zeng, Liang Guo, De-Feng Zhang, Hui-Ming Dai, Guo-Nan Chen, Electroanalysis, 2007, 19(21): 2251-2257.

其它论文：

5.3D Nanoporous Gold-Supported Pt Nanoparticles as Highly Accelerating Catalytic Au-Pt Micromotors，Jin-Zhi Jiang, Ling-Qing Ren, Yu-Ping Huang, Xiao-Dong Li, Shao-Hua Wu, and Jian-Jun Sun*, Adv. Mater. Interfaces, 2018, 1701689

4.Molar Range Detection Based on Sideband Differential Absorption Spectroscopy with a Concentrated Reference，Liu-Chuang Zhao, Mei-Hong Guo, Xiao-Dong Li, Yu-Ping Huang, Shao-Hua Wu, and Jian-Jun Sun*, Anal. Chem. 2017, 89, 13429−13433

3.A model for understanding the temperature change of an alternate hot and cold micro-band graphite electrode, Sen Yang, Zong-Xiong Huang, Xiao-Heng Hou, Fang-Fang Cheng, Shao-Hua Wu, Jian-Jun Sun*, Electrochemistry Communications, 2016, 68, 71 –75.

2.Alternate hot and cold electrodes，Zong-Xiong Huang, Sen Yang, Fen-Zeng Yao, Kai-Xuan Xu, Ji-Fang Zhang, Shao-Hua Wu, Jian-Jun Sun*, Electrochemistry Communications, 2015, 61, 129–133.

1.Supercooled electrodes, Zong-Xiong Huang, Sen Yang, Jun-Wei Guo, Shao-Hua Wu, Jian-Jun Sun*, Guo-Nan Chen, Electrochemistry Communications, 2014, 48, 107–110.

获授权专利：

一种温度可控基于酶催化的电化学过氧化氢传感器，发明专利

专利号：201611174258.9

一种温度可控的电化学DNA生物传感器及其制备方法，发明专利

专利号：201611120926.X

一种温度可控过氧化氢传感器，实用新型专利

专利号：ZL 2015 2 0089159.5

获奖情况

2022年福州大学优秀硕士学位论文（指导教师）

2022年福州大学优秀硕士学位论文（指导教师）

2022年研究生综合学业奖学金特等奖（指导教师）

2022年研究生综合学业奖学金特等奖（指导教师）

2022年福州大学化学学院“杨洪耀奖教金”

2021年福州大学教学优秀奖二等奖

2021年第四届福州大学“福能奖教金”

2021年福州大学优秀硕士学位论文（指导教师）

2021年福州大学优秀本科毕业论文（指导教师）

2018年福州大学本科教学成果奖二等奖（排名第二）

2018年福州大学教学优秀奖二等奖

2018年国家优秀研究生奖学金（指导教师）

2018年福州大学研究生中期优秀学业奖学金一等奖（指导教师）

2017年福州大学本科教学成果奖一等奖（排名第四）

2016年第十届全国大学生化学实验邀请赛二等奖（指导教师）

2015年国家优秀研究生奖学金（指导教师）

 

其他