教育工作经历

 2018.03-                 福州大学，教授、博士生导师

 2014.06-2018.02   美国，国立卫生研究院，博士后

 2010.08-2014.07    新加坡，南洋理工大学，博士 

教学简介

    本科生《仪器分析》

    研究生《高等分析化学》

    研究生《高等分析化学实验》

科研简介  

主要研究内容包括：分子探针制备、生物传感、分子影像，生物医学工程、医学检测、新型药物载体等。累计发表SCI论文 110 余篇，其中以通讯/第一作者发表的影响因子大于10分的文章为 50余 篇，主要包括 Nat. Protoc.(1篇), Nat. Commoun. (3篇). J. Am. Chem. Soc.(5 篇), Angew. Chem. Int. Ed. (8篇), Adv. Mater. (6 篇), ACS Nano (10 篇), Adv. Funct. Mater. (7篇),  Chem. Soc. Rev. (3 篇), Acc. Chem. Res. (1 篇) 等。

社会兼职

   《Journal of Biomedical and Allied Research》期刊副主编

   《当代化工研究》期刊编委

科研项目

      “海外高层次引进人才” 人才项目（2018-2020）

     福建省 “闽江学者” 特聘教授科研启动基金 （2018-2021）

     国家自然科学基金委面上项目 （201901-2022.12）

     福建省卫生健康委员会联合攻关项目（2020.01-2022.12）

     福建省自然科学基金重点项目  （2020.09-20223.11）

代表性论文

       2021--

          (1)  Li, Q.; Ge, X.; Ye, J.; Li, Z.; Su, L.; Wu, Y.; Yang, H.; Song, J.*, Dual Ratiometric SERS and Photoacoustic Core-Satellite Nanoprobe for Quantitatively Visualizing Hydrogen Peroxide in Inflammation and Cancer. Angew. Chem. Int. Ed. 2021, 133, 2-12

        (2)  Wang, C.; Lin, H.; Ge, X.; Mu, J.; Su, L.; Zhang, X.; Niu, M.; Yang, H.; Song, J.*, Dye‐Sensitized Downconversion Nanoprobes with Emission Beyond 1500 nm for Ratiometric Visualization of Cancer Redox State. Adv. Funct. Mater. 2021, 10.1002/adfm.202009942.

 (3)   Feng, H.; Fu, Q.; Du, W.; Zhu, R.; Ge, X.; Wang, C.; Li, Q.; Su, L.; Yang, H.; Song, J.*, Quantitative Assessment of Copper (II) in Wilson's Disease Based on Photoacoustic Imaging and Ratiometric Surface-Enhanced Raman Scattering. ACS Nano 2021, 10.1021/acsnano.0c10407.

(4)  Fu, Q.; Ye, J.; Wang, J.; Liao, N.; Feng, H.; Su, L.; Ge, X.; Yang, H.; Song, J.* NIR-II Photoacoustic Reporter for Biopsy-Free and Real-Time Assessment of Wilson’s Disease. Small 2021, 10.1002/smll.202008061.

(5)   Fu, Q.; Li, Z.; Fu, F.; Chen, X.*; Song, J.*; Yang, H.*, Stimuli-Responsive Plasmonic Assemblies and Their Biomedical Applications. Nano Today 2021, 36，101014.

(6)  Liao, N.; Zhang, D.; Wu, M.; Yang, H.; Liu, X.*; Song, J.*, Enhancing therapeutic effects and in vivo tracking of adipose tissue-derived mesenchymal stem cells for liver injury using bioorthogonal click chemistry. Nanoscale 2021, 13 (3), 1813-1822.

(7)  Tang, W.; Yang, Z.; He, L.; Deng, L.; Fathi, P.; Zhu, S.; Li, L.; Shen, B.; Wang, Z.; Jacobson, O.; Song, J.; Zou, J.; Hu, P.; Wang, M.; Mu, J.; Cheng, Y.; Ma, Y.; Tang, L.; Fan, W.; Chen, X., A hybrid semiconducting organosilica-based O2 nanoeconomizer for on-demand synergistic photothermally boosted radiotherapy. Nat. Commun. 2021, 12 (1), 523.

      2020年度

(1) Zhao, C.; Chen, J.; Zhong, R.; Chen, D. S.; Shi, J.*; Song, J.*, Oxidative-Species-Selective Materials for Diagnostic and Therapeutic Applications. Angew. Chem. Int. Ed.2020,  10.1002/anie.201915833.  

(2)  Li, Z.; Fu, Q.; Ye, J.; Ge, X.; Wang, J.; Song, J.*; Yang, H.*, Ag(+) -Coupled Black Phosphorus Vesicles with Emerging NIR-II Photoacoustic Imaging Performance for Cancer Immune-Dynamic Therapy and Fast Wound Healing. Angew. Chem. Int. Ed.2020, 59 (49), 22202-22209.

(3)  Lin, X.; Liu, S.; Zhang, X.; Zhu, R.; Chen, S.; Chen, X.; Song, J.*; Yang, H.*, An Ultrasound Activated Vesicle of Janus Au-MnO Nanoparticles for Promoted Tumor Penetration and Sono-Chemodynamic Therapy of Orthotopic Liver Cancer. Angew. Chem. Int. Ed.2020, 59 (4), 1682-1688.

(4)  Deng, H.; Yang, W.; Zhou, Z.; Tian, R.; Lin, L.; Ma, Y.; Song, J.*; Chen, X.*, Targeted scavenging of extracellular ROS relieves suppressive immunogenic cell death. Nat. Commun. 2020, 11 (1), 4951.

(5) Lin, H.; Yang, L.; Zhang, X.; Liu, G.; Zhuo, S.; Chen, J.; Song, J.*, Emerging Low‐Dimensional Nanoagents for Bio‐Microimaging. Adv. Funct. Mater.2020, 30 (40).

 (6)  Zhu, R.; Li, J.; Lin, L.*; Song, J.*; Yang, H.*, Emerging Plasmonic Assemblies Triggered by DNA for Biomedical Applications. Adv. Funct. Mater. 2020, e2005709.

(7 )Lian, W.; Tu, D.*; Hu, P.; Song, X.; Gong, Z.; Chen, T.; Song, J.; Chen, Z.; Chen, X.*, Broadband excitable NIR-II luminescent nano-bioprobes based on CuInSe2 quantum dots for the detection of circulating tumor cells. Nano Today2020, 35，100943.

(8)  Song, X.; Zhu, W.; Ge, X.; Li, R.; Li, S.; Chen, X.; Song, J.; Xie, J.*; Chen, X.*; Yang, H.*, A New Class of NIR-II Gold Nanocluster-Based Protein Biolabels for In Vivo Tumor-Targeted Imaging. Angew. Chem. Int. Ed.2021, 60 (3), 1306-1312.

(9)  Dai, J.; Yao, L.; Gao, X.; Bai, S.; Chen, X.; Li, L.*; Song, J.*; Yang, H., To achieve ultrasensitive electrochemical detection of mercury ions employing metallic 1T-MoS2 nanosheets. Electrochim. Acta2020, 355.

(10)  Lin, L.; Wang, S.; Deng, H.; Yang, W.; Rao, L.; Tian, R.; Liu, Y.; Yu, G.; Zhou, Z.; Song, J.; Yang, H. H.; Chen, Z. Y.*; Chen, X.*, Endogenous Labile Iron Pool-Mediated Free Radical Generation for Cancer Chemodynamic Therapy. J. Am. Chem. Soc.2020, 142 (36), 15320-15330.

(11) Chen, T.; Su, L.; Ge, X.; Zhang, W.; Li, Q.; Zhang, X.; Ye, J.; Lin, L.; Song, J.*; Yang, H.*, Dual activated NIR-II fluorescence and photoacoustic imaging-guided cancer chemo-radiotherapy using hybrid plasmonic-fluorescent assemblies. Nano Research2 020, 13 (12), 3268-3277.

(12) Zhang, D.; Lin, Z.; Zheng, Y.; Song, J.; Li, J.; Zeng, Y.*; Liu, X.*, Ultrasound-Driven Biomimetic Nanosystem Suppresses Tumor Growth and Metastasis through Sonodynamic Therapy, CO Therapy, and Indoleamine 2,3-Dioxygenase Inhibition.ACS Nano2020, 14 (7), 8985-8999.

(13) Ye, J.; Li, Z.; Fu, Q.; Li, Q.; Zhang, X.; Su, L.; Yang, H.; Song, J.*, Quantitative Photoacoustic Diagnosis and Precise Treatment of Inflammation In Vivo Using Activatable Theranostic Nanoprobe. Adv. Funct. Mater. 2020, 30 (38),2001771.

(14) Li, S.; Song, X.; Zhu, W.; Chen, Y.; Zhu, R.; Wang, L.; Chen, X.; Song, J.*; Yang, H.*, Light-Switchable Yolk-Mesoporous Shell UCNPs@MgSiO3 for Nitric Oxide-Evoked Multidrug Resistance Reversal in Cancer Therapy. ACS Appl. Mater. Interfaces2020, 12 (27), 30066-30076.

(15) Wang, Z.; Sun, X.; Huang, T.; Song, J.*; Wang, Y.*, A Sandwich Nanostructure of Gold Nanoparticle Coated Reduced Graphene Oxide for Photoacoustic Imaging-Guided Photothermal Therapy in the Second NIR Window. Front Bioeng Biotechnol2020, 8, 655.

(16) Zhang, W.; Wang, J.; Su, L.; Chen, H.; Zhang, L.; Lin, L.; Chen, X.; Song, J.*; Yang, H.*, Activatable nanoscale metal-organic framework for ratiometric photoacoustic imaging of hydrogen sulfide and orthotopic colorectal cancer in vivo. Sci. China: Chem. 2020, 63 (9), 1315-1322.

(17) Zhou, Z.; Deng, H.; Yang, W.; Wang, Z.; Lin, L.; Munasinghe, J.; Jacobson, O.; Liu, Y.; Tang, L.; Ni, Q.; Kang, F.; Liu, Y.; Niu, G.; Bai, R.; Qian, C.; Song, J.*; Chen, X.*, Early stratification of radiotherapy response by activatable inflammation magnetic resonance imaging.Nat. Commun.2020, 11 (1), 3032.

(18)  Lin, X.; Song, J.*; Chen, X.*; Yang, H.*, Ultrasound-Activated Sensitizers and Applications. Angew. Chem. Int. Ed.2020, 59 (34), 14212-14233.

(19) Zhu, R.; Su, L.; Dai, J.; Li, Z.-W.*; Bai, S.; Li, Q.; Chen, X.; Song, J.*; Yang, H.*, Biologically Responsive Plasmonic Assemblies for Second Near-Infrared Window Photoacoustic Imaging-Guided Concurrent Chem-Immunotherapy. ACS Nano2020, 10.1021/acsnano.9b07984.

(20) Zhang, W.; Chen, T.; Su, L.; Ge, X.; Chen, X.; Song, J.*; Yang, H.*, Quantum Dot-Based Sensitization System for Boosted Photon Absorption and Enhanced Second Near-Infrared Luminescence of Lanthanide-Doped Nanoparticle. Anal. Chem.2020, 92 (8), 6094-6102.

(21)  Ge, X.; Lou, Y.; Su, L.; Chen, B.; Guo, Z.*; Gao, S.*; Zhang, W.; Chen, T.; Song, J*.; Yang, H., Single Wavelength Laser Excitation Ratiometric NIR-II Fluorescent Probe for Molecule Imaging in Vivo. Anal. Chem. 2020, 92 (8), 6111-6120.

(22)  Deng, H.; Zhou, Z.; Yang, W.; Lin, L. S.; Wang, S.; Niu, G.; Song, J.*; Chen, X.*, Endoplasmic Reticulum Targeting to Amplify Immunogenic Cell Death for Cancer Immunotherapy. Nano Lett.. 2020, 20 (3), 1928-1933.

(23)  Cao, J.*; Zhu, B.; Zheng, K.; He, S.; Meng, L.; Song, J.*; Yang, H.*, Recent Progress in NIR-II Contrast Agent for Biological Imaging. Front Bioeng Biotechnol 2019, 7, 487.

(24)  Fu, Q.; Li, Z.; Ye, J.; Li, Z.; Fu, F.; Lin, S. L.; Chang, C. A.; Yang, H.; Song, J.*, Magnetic targeted near-infrared II PA/MR imaging guided photothermal therapy to trigger cancer immunotherapy. Theranostics2020, 10 (11), 4997-5010.

(25)  Ge, X.; Fu, Q.; Su, L.; Li, Z.; Zhang, W.; Chen, T.; Yang, H.; Song, J.*, Light-activated gold nanorod vesicles with NIR-II fluorescence and photoacoustic imaging performances for cancer theranostics.Theranostics2020, 10 (11), 4809-4821.

2019年度

(1) Song, J.; Lin, L.; Yang, Z.; Zhu, R.; Zhou, Z.; Li, Z.-W.; Wang, F.; Chen, J.; Yang, H.; Chen, X. Self-Assembled Responsive Bilayered Vesicles with Adjustable Oxidative Stress for Enhanced Cancer Imaging and Therapy. Journal of the American Chemical Society 2019, 141 (20), 8158-8170.

(2) Lin, X.; Song, J.* Chen, X.;* Yang, H.* Ultrasound Activated Sensitizers and Applications. Angew. Chem. Int. Ed. 2019. 10.1002/anie.201906823

(3)  Fu, Q.; Zhu, R.; Song, J.;* Yang, H.;* Chen, X.* Photoacoustic Imaging: Contrast Agents and Their Biomedical Applications. Adv. Mater.2019, 31, e1805875.

(4) Deng, H.; Lin, L.; Wang, S.; Yu, G.; Zhou, Z.; Liu, Y.; Niu, G.; Song, J.;* Chen, X.* X-ray-Controlled Bilayer Permeability of Bionic Nanocapsules Stabilized by Nucleobase Pairing Interactions for Pulsatile Drug Delivery. Adv. Mater. 2019, 31 (37), 1903443.

(5)Liu, T. J.; Tong, L. L.; Lv, N. N.; Ge, X. G.; Fu, Q. R.; Gao, S.; Ma, Q. E.; Song, J. B.,* Two-Stage Size Decrease and Enhanced Photoacoustic Performance of Stimuli-Responsive Polymer-Gold Nanorod Assembly for Increased Tumor Penetration. Advanced Functional Materials 2019, 29 (16), 1806429.

(6) Li, Z.; Hu, Y.; Fu, Q.; Liu, Y.; Wang, J.; Song, J.;* Yang, H.* NIR/ROS‐Responsive Black Phosphorus QD Vesicles as Immunoadjuvant Carrier for Specific Cancer Photodynamic Immunotherapy. Advanced Functional Materials 2019, 1905758.

(7) Chen, L.;* Zhou, S. F.; Su, L.; Song, J.;* Gas-Mediated Cancer Bioimaging and Therapy. ACS Nano 2019.

(8) Li, S.; Liu, R.; Jiang, X.; Qiu, Y.; Song, X.; Huang, G.; Fu, N.; Lin, L.; S Song, J.;* Chen, X.;* Yang, H.* Near-Infrared Light-Triggered Sulfur Dioxide Gas Therapy of Cancer. ACS Nano 2019.

(9)Yang, L.; Zhou, Z.; Song, J.;* Chen, X.* Anisotropic nanomaterials for shape-dependent physicochemical and biomedical applications. Chem. Soc. Rev. 2019.

(10) Wu, Y.; Song, J.;* Chen, X.;* Yang, H.* Hydrogen Gas from Inflammation Treatment to Cancer Therapy, ACS Nano, 2019, 13, 8505

(11) Yang, Z.;^# Song, J.;^# Tang, W.; Fan, W.; Dai, Y.; Shen, Z.; Lin, L.; Cheng, S.; Liu, Y.; Niu, G.; Rong, P.; Wang, W.; Chen, X., Stimuli-Responsive Nanotheranostics for Real-Time Monitoring Drug Release by Photoacoustic Imaging. Theranostics 2019, 9 (2), 526-536.

(12) Lin, X.; Qiu, Y.; Song, L.; Chen, S.; Chen, X.; Huang, G.; Song, J.;* Chen, X.; Yang, H. Ultrasound activation of liposomes for enhanced ultrasound imaging and synergistic gas and sonodynamic cancer therapy. Nanoscale Horizons 2019.

(13) Li, Z.; Guo, T.; Hu, Y.; Qiu, Y.; Liu, Y.; Wang, H.; Li, Y.; Chen, X.; Song, J.;* Yang, H.* A Highly Effective π-π Stacking Strategy to Modify Black Phosphorus with Aromatic Molecules for Cancer Theranostics. ACS Appl. Mat. Interfaces2019.

 (14) Guo, T.; Lin, Y.; Jin, G.; Weng, R.; Song, J.; Liu, X.; Huang, G.; Hou, L.; Yang, H. Manganese-phenolic network-coated black phosphorus nanosheets for theranostics combining magnetic resonance/photoacoustic dual-modal imaging and photothermal therapy. Chemical Communications 2019, 55, 850-853.

 (15) Deng, H.; Dong, A.; Song, J.;* Chen, X.* Injectable thermosensitive hydrogel systems based on functional PEG/PCL block polymer for local drug delivery. Journal of Controlled Release 2019, 297, 60-70.

(16) Ge, X.; Fu, Q.; Bai, L.; Chen, B.; Wang, R.; Gao, S.; Song, J.* Photoacoustic imaging and photothermal therapy in the second near-infrared window. New J. Chem. 2019.

2018年度

   (1)  Yu, G.; Yang, J.; Fu, X.; Wang, Z.; Shao, L.; Mao, Z.; Liu, Y.; Yang, Z.; Zhang, F.; Fan, W.; Song, J.; Zhou, Z.; Gao, C.; Huang, F.; Chen, X. A supramolecular hybrid material constructed from graphene oxide and a pillar[6]arene-based host–guest complex as an ultrasound and photoacoustic signal nanoamplifier. Materials Horizons 2018, 5, 429-435.

    (2)  Yang, Z.; Fan, W.; Tang, W.; Shen, Z.; Dai, Y.; Song, J.; Wang, Z.; Liu, Y.; Lin, L.; Shan, L.; Liu, Y.; Jacobson, O.; Rong, P.; Wang, W.; Chen, X. Hybrid of Near-Infrared Semiconducting Polymer Brush and pH/GSH-responsive Polyoxometalate Cluster for Enhanced Tumor-Specific Phototheranostics. Angew Chem Int Ed Engl 2018.

       (3)  Yang, Z.; Dai, Y.; Yin, C.; Fan, Q.; Zhang, W.; Song, J.; Yu, G.; Tang, W.; Fan, W.; Yung, B. C.; Li, J.; Li, X.; Li, X.; Tang, Y.; Huang, W.; Song, J.; Chen, X. Activatable Semiconducting Theranostics: Simultaneous Generation and Ratiometric Photoacoustic Imaging of Reactive Oxygen Species In Vivo. Adv. Mater. 2018, 30, e1707509.

       (4)  Shen, Z.; Song, J.; Zhou, Z.; Yung, B. C.; Aronova, M. A.; Li, Y.; Dai, Y.; Fan, W.; Liu, Y.; Li, Z.; Ruan, H.; Leapman, R. D.; Lin, L.; Niu, G.; Chen, X.; Wu, A. Dotted Core-Shell Nanoparticles for T1 -Weighted MRI of Tumors. Adv. Mater. 2018, 30, e1803163.

       (5)  Shen, Z.; Song, J.; Yung, B. C.; Zhou, Z.; Wu, A.; Chen, X. Emerging Strategies of Cancer Therapy Based on Ferroptosis. Adv. Mater. 2018, 30, e1704007.

       (6)  Lin, L.-S.;# Song, J.;# Song, L.; Ke, K.; Liu, Y.; Zhou, Z.; Shen, Z.; Li, J.; Yang, Z.; Tang, W.; Niu, G.; Yang, H.-H.; Chen, X. Simultaneous Fenton-like Ion Delivery and Glutathione Depletion by MnO2-Based Nanoagent to Enhance Chemodynamic Therapy. Angewandte Chemie-International Edition 2018, 57, 4902-4906.

       (7)  Lin, L. S.; Song, J.;* Yang, H. H.; Chen, X. Yolk-Shell Nanostructures: Design, Synthesis, and Biomedical Applications. Adv. Mater. 2018, 30, 1704639.

       (8)  Huang, X.-W.; Wei, J.-J.; Zhang, M.-Y.; Zhang, X.-L.; Yin, X.-F.; Lu, C.-H.; Song, J.-B.; Bai, S.-M.; Yang, H.-H. Water-Based Black Phosphorus Hybrid Nanosheets as a Moldable Platform for Wound Healing Applications. ACS Appl. Mat. Interfaces 2018, 10, 35495-35502.

       (9)  Huang, X.; Song, J.;* Yung, B. C.; Huang, X.; Xiong, Y.; Chen, X. Ratiometric optical nanoprobes enable accurate molecular detection and imaging. Chem. Soc. Rev. 2018, 47, 2873-2920.

       (10) Huang, X.; Liu, Y.; Barr, J.; Song, J.; He, Z.; Wang, Y.; Nie, Z.; Xiong, Y.; Chen, X. Controllable self-assembled plasmonic vesicle-based three-dimensional SERS platform for picomolar detection of hydrophobic contaminants. Nanoscale 2018, 10, 13202-13211.

2017年度

       (1)  Zhou, Z.; Tian, R.; Wang, Z.; Yang, Z.; Liu, Y.; Liu, G.; Wang, R.; Gao, J.; Song, J.;* Nie, L.; Chen, X. Artificial local magnetic field inhomogeneity enhances T2 relaxivity. Nat Commun 2017, 8, 15468.

       (2)  Zhou, Z.; Song, J.;# Tian, R.; Yang, Z.; Yu, G.; Lin, L.; Zhang, G.; Fan, W.; Zhang, F.; Niu, G.; Nie, L.; Chen, X. Activatable Singlet Oxygen Generation from Lipid Hydroperoxide Nanoparticles for Cancer Therapy. Angew Chem Int Ed Engl 2017, 56, 6492-6496.

       (3) Yang, Z.; Tian, R.; Wu, J.; Fan, Q.; Yung, B. C.; Niu, G.; Jacobson, O.; Wang, Z.; Liu, G.; Yu, G.; Huang, W.; Song, J.;* Chen, X. Impact of Semiconducting Perylene Diimide Nanoparticle Size on Lymph Node Mapping and Cancer Imaging. ACS Nano 2017, 11, 4247-4255.

       (4)  Yang, Z.; Song, J.;* Dai, Y.; Chen, J.; Wang, F.; Lin, L.; Liu, Y.; Zhang, F.; Yu, G.; Zhou, Z.; Fan, W.; Huang, W.; Fan, Q.; Chen, X. Self-Assembly of Semiconducting-Plasmonic Gold Nanoparticles with Enhanced Optical Property for Photoacoustic Imaging and Photothermal Therapy. Theranostics 2017, 7, 2177-2185.

       (5) Yang, X.; Wang, Z.; Zhang, F.; Zhu, G.; Song, J.; Teng, G.-J.; Niu, G.; Chen, X. Mapping Sentinel Lymph Node Metastasis by Dual-probe Optical Imaging. Theranostics 2017, 7, 153.

       (6)  Song, J.; Yang, X.; Yang, Z.; Lin, L.; Liu, Y.; Zhou, Z.; Shen, Z.; Yu, G.; Dai, Y.; Jacobson, O.; Munasinghe, J.; Yung, B.; Teng, G. J.; Chen, X. Rational Design of Branched Nanoporous Gold Nanoshells with Enhanced Physico-Optical Properties for Optical Imaging and Cancer Therapy. ACS Nano 2017, 11, 6102-6113.

       (7)  Song, J.; Wu, B.; Zhou, Z.; Zhu, G.; Liu, Y.; Yang, Z.; Lin, L.; Yu, G.; Zhang, F.; Zhang, G.; Duan, H.; Stucky, G. D.; Chen, X. Double-Layered Plasmonic-Magnetic Vesicles by Self-Assembly of Janus Amphiphilic Gold-Iron(II,III) Oxide Nanoparticles. Angew Chem Int Ed Engl 2017, 56, 8110-8114.

       (8)  Song, J.; Niu, G.; Chen, X. Amphiphilic-Polymer-Guided Plasmonic Assemblies and Their Biomedical Applications. Bioconjug Chem 2017, 28, 105-114.

       (9)  Shen, Z.; Chen, T.; Ma, X.; Ren, W.; Zhou, Z.; Zhu, G.; Zhang, A.; Liu, Y.; Song, J.;* Li, Z.; Ruan, H.; Fan, W.; Lin, L.; Munasinghe, J.; Chen, X.; Wu, A. Multifunctional Theranostic Nanoparticles Based on Exceedingly Small Magnetic Iron Oxide Nanoparticles for T1-Weighted Magnetic Resonance Imaging and Chemotherapy. ACS Nano 2017, 11, 10992-11004.

       (10) Lin, L. S.; Yang, X.; Zhou, Z.; Yang, Z.; Jacobson, O.; Liu, Y.; Yang, A.; Niu, G.; Song, J.;* Yang, H. H.; Chen, X. Yolk-Shell Nanostructure: An Ideal Architecture to Achieve Harmonious Integration of Magnetic-Plasmonic Hybrid Theranostic Platform. Adv. Mater. 2017, 29, 1606681.

       (11) Chen, L. C.; Song, J.;* Tailored Graphitic Carbon Nitride Nanostructures: Synthesis, Modification, and Sensing Applications. Advanced Functional Materials 2017, 27, 1702695.

       (12) Zhou, Z.; Song, J.; Nie, L.; Chen, X. Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy. Chemical Society Reviews 2016, 45, 6597-6626.

2016年度

       (1)  Tong, X.; Wang, Z.; Sun, X.; Song, J.; Jacobson, O.; Niu, G.; Kiesewetter, D. O.; Chen, X. Size Dependent Kinetics of Gold Nanorods in EPR Mediated Tumor Delivery. Theranostics 2016, 6, 2039-2051.

       (2)  Song, J.; Wang, F.; Yang, X.; Ning, B.; Harp, M. G.; Culp, S. H.; Hu, S.; Huang, P.; Nie, L.; Chen, J.; Chen, X. Gold Nanoparticle Coated Carbon Nanotube Ring with Enhanced Raman Scattering and Photothermal Conversion Property for Theranostic Applications. Journal of the American Chemical Society 2016, 138, 7005–7015.

       (3)  Song, J.; Huang, P.; Chen, X. Jibin*  Preparation of plasmonic vesicles from amphiphilic gold nanocrystals grafted with polymer brushes. Nat. Protoc. 2016, 11, 2287-2299.

       (4)  Song, J.; Hu, H.; Jian, C.; Wu, K.; Chen, X. New Generation of Gold Nanoshell-Coated Esophageal Stent: Preparation and Biomedical Applications. ACS Appl. Mat. Interfaces 2016, 8, 27523-27529.

       (5)  Liu, Y.; Wang, Z.; Zhang, H.; Lang, L.; Ma, Y.; He, Q.; Lu, N.; Huang, P.; Song, J.; Liu, Z.; Gao, S.; Ma, Q.; Kiesewetter, D. O.; Chen, X. A photothermally responsive nanoprobe for bioimaging based on Edman degradation. Nanoscale 2016, 8, 10553-10557.

       (6)  Lin, L.-S.; Yang, X.; Niu, G.; Song, J.;* Yang, H.-H.; Chen, X. Dual-enhanced photothermal conversion properties of reduced graphene oxide-coated gold superparticles for light-triggered acoustic and thermal theranostics. Nanoscale 2016, 8, 2116-2122.

       (7)  Lin, J.; Wang, M.; Hu, H.; Yang, X.; Wen, B.; Wang, Z.; Jacobson, O.; Song, J.; Zhang, G.; Niu, G.; Huang, P.; Chen, X. Multimodal-Imaging-Guided Cancer Phototherapy by Versatile Biomimetic Theranostics with UV and gamma-Irradiation Protection. Adv. Mater. 2016, 28, 3273-3279.

       (8)  Huang, P.; Ling, D. S.; Song, J. B.; Liu, G.; Xie, J. Nanomaterials for Cancer Phototheranostics. Journal of Nanomaterials 2016, 2016.

       (9)  Fan, J.; Song, J.; Liu, Y.; Yu, G.; Ma, Y.; Deng, Y.; He, N.; Zhang, F. Synthesis of biocompatible polymeric nanomaterial dually loaded with paclitaxel and nitric oxide for anti-MDR cancer therapy. RSC Advances 2016, 6, 105871-105877.

       (10) Fan, J.; He, Q.; Liu, Y.; Zhang, F.; Yang, X.; Wang, Z.; Lu, N.; Fan, W.; Lin, L.; Niu, G.; He, N.; Song, J.;* Chen, X. Light-Responsive Biodegradable Nanomedicine Overcomes Multidrug Resistance via NO-Enhanced Chemosensitization. ACS Appl. Mat. Interfaces 2016, 8 13804–13811.

2015年度

       (1)  Tang, Y.; Hu, H.; Zhang, M. G.; Song, J.; Nie, L.; Wang, S.; Niu, G.; Huang, P.; Lu, G.; Chen, X. An aptamer-targeting photoresponsive drug delivery system using "off-on" graphene oxide wrapped mesoporous silica nanoparticles. Nanoscale 2015, 7, 6304-6310.

       (2)  Song, J.; Yang, X.; Jacobson, O.; Lin, L.; Huang, P.; Niu, G.; Ma, Q.; Chen, X. Sequential Drug Release and Enhanced Photothermal and Photoacoustic Effect of Hybrid Reduced Graphene Oxide-Loaded Ultrasmall Gold Nanorod Vesicles for Cancer Therapy. ACS Nano 2015, 9, 9199-9209.

       (3)  Song, J.; Yang, X.; Jacobson, O.; Huang, P.; Sun, X.; Lin, L.; Yan, X.; Niu, G.; Ma, Q.; Chen, X. Ultrasmall Gold Nanorod Vesicles with Enhanced Tumor Accumulation and Fast Excretion from the Body for Cancer Therapy. Adv. Mater. 2015, 27, 4910-4917.

       (4)  Song, J.; Huang, P.; Duan, H.; Chen, X. Plasmonic Vesicles of Amphiphilic Nanocrystals: Optically Active Multifunctional Platform for Cancer Diagnosis and Therapy. Acc. Chem. Res. 2015, 48, 2506-2515.

       (5)  Huang, P.; Gao, Y.; Lin, J.; Hu, H.; Liao, H.-S.; Yan, X.; Tang, Y.; Jin, A.; Song, J.; Niu, G.; Zhang, G.; Horkay, F.; Chen, X. Tumor-Specific Formation of Enzyme-Instructed Supramolecular Self-Assemblies as Cancer Theranostics. ACS Nano 2015, 9, 9517-9527.

2010-2014年度

    (1)  Zhou, J.; Duan, B.; Fang, Z.; Song, J.; Wang, C.; Messersmith, P. B.; Duan, H. Interfacial assembly of mussel-inspired au@ag@ polydopamine core-shell nanoparticles for recyclable nanocatalysts. Adv. Mater. 2014, 26, 701-705.

     (2)  Song, J.; Duan, B.; Wang, C.; Zhou, J.; Pu, L.; Fang, Z.; Wang, P.; Lim, T. T.; Duan, H. SERS-encoded nanogapped plasmonic nanoparticles: growth of metallic nanoshell by templating redox-active polymer brushes. Journal of the American Chemical Society 2014, 136, 6838-6441.

     (3)  Wang, C.; Du, Y.; Wu, Q.; Xuan, S.; Zhou, J.; Song, J.; Shao, F.; Duan, H. Stimuli-responsive plasmonic core-satellite assemblies: i-motif DNA linker enabled intracellular pH sensing. Chemical Communications 2013, 49, 5739-5741.

    (4)  Song, J.; Pu, L.; Zhou, J.; Duan, B.; Duan, H. Biodegradable Theranostic Plasmonic Vesicles of Amphiphilic Gold Nanorods. ACS Nano 2013, 7 9947–9960.

    (5)  Song, J.; Fang, Z.; Wang, C.; Zhou, J.; Duan, B.; Pu, L.; Duan, H. Photolabile plasmonic vesicles assembled from amphiphilic gold nanoparticles for remote-controlled traceable drug delivery. Nanoscale 2013, 5, 5816-5824.

    (6)  Fang, Z.; Wang, Y.; Song, J.; Sun, Y.; Zhou, J.; Xu, R.; Duan, H. Immobilizing CdS quantum dots and dendritic Pt nanocrystals on thiolated graphene nanosheets toward highly efficient photocatalytic H2 evolution. Nanoscale 2013, 5, 9830-9838.

    (7)  Song, J.; Zhou, J.; Duan, H. Self-Assembled Plasmonic Vesicles of SERS-Encoded Amphiphilic Gold Nanoparticles for Cancer Cell Targeting and Traceable Intracellular Drug Delivery. Journal of the American Chemical Society 2012, 134, 13458-13469.

    (8)  Yin, J.; Wu, T.; Song, J.; Zhang, Q.; Liu, S.; Xu, R.; Duan, H. SERS-Active Nanoparticles for Sensitive and Selective Detection of Cadmium Ion (Cd2+). Chemistry of Materials 2011, 23, 4756-4764.

   (9)  Xiao, F.; Song, J.;Gao, H.; Zan, X.; Xu, R.; Duan, H. Coating Graphene Paper with 2D-Assembly of Electrocatalytic Nanoparticles: A Modular Approach toward High-Performance Flexible Electrodes. ACS Nano 2011, 6, 100–110.

   (10) Song, J.; Cheng, L.; Liu, A.; Yin, J.; Kuang, M.; Duan, H. Plasmonic Vesicles of Amphiphilic Gold Nanocrystals: Self-Assembly and External-Stimuli-Triggered Destruction. Journal of the American Chemical Society 2011, 133, 10760-10763.

  (11) Cheng, L.; Song, J.; Yin, J.; Duan, H. W. Self-Assembled Plasmonic Dimers of Amphiphilic Gold Nanocrystals. J. Phys. Chem. Lett. 2011, 2, 2258-2262.

  (12) Chen, Z. J.; Yu, D. X.; Liu, C. X.; Yang, X. Y.; Zhang, N.; Ma, C. H.; Song, J.; Lu, Z. J. Gadolinium-conjugated PLA-PEG nanoparticles as liver targeted molecular MRI contrast agent. Journal of drug targeting 2011, 19, 657-665.

专利

1.Song, J. B, Lu, Z. J. Facile Synthesis of Primary amino-functionized poly(ethylene glycol)-poly(lactic acid) block copolymer (H₂N-PEG-b-PLA). 2009, CN: 101555316 A.

2.Song, J. B, Lu, Z. J. Guangzhao Zhang, Na Zhang. An amphiphilic block copolymer Synthesis and its nanoparticle preparation. 2009, CN: 101565497.

3.Song, J. B, Chen, X. Y. Vesicle Containing Metallic Nanoparticle and Method for Production. Application No. USA62/266,289.

获奖情况

   美国国立卫生研究院 “杰出博士后研究员”

   优秀海外博士留学生奖学金

其他

    课题组常年招收分析化学，材料工程，生物医学等相关专业的硕士、博士、科研助理、博士后，待遇优厚。有意向者请发送简历至邮箱：jibinsong@fzu.edu.cn。