教育工作经历

05/2019至今          福州大学化学学院，“闽江学者”特聘教授

04/2017-05/2019   博士后, 康奈尔大学 (Cornell University), 美国

                              合作导师: Song Lin教授

                              研究方向: 催化电化学合成

10/2014-03/2017   博士后, 明斯特大学 (Universität Münster), 德国

                              合作导师: Gerhard Erker教授

                              研究方向: 受阻路易斯酸碱对 (FLPs) 参与的小分子活化与催化

09/2009-07/2014   博士, 中国科学院上海有机化学研究所

                              导师: 戴立信 院士 & 游书力 研究员

                              论文: 金属铱催化的烯丙基取代反应：手性杂环的合成和催化剂设计

09/2005-07/2009   本科, 厦门大学 化学化工学院化学系

                              导师: 黄培强 教授 & 张洪奎 教授

                              论文: 天然产物 (+)-Preussin的合成

教学简介

科研简介   

1. 电化学合成

2. 不对称催化

3. 药物化学
 

社会兼职

科研项目

代表性论文  

1. 1. Ke-Yin Ye, #Terry McCallum, #Song Lin*; Bimetallic Radical Redox-Relay Catalysis for the Isomerization of Epoxides to Allylic Alcohols. J. Am. Chem. Soc. 2019, 141, 9548.(# equal contribution)

2. 2. Ke-Yin Ye, Gisselle Pombar, Niankai Fu, Gregory S Sauer, Ivan Keresztes, Song Lin*; Anodically Coupled Electrolysis for the Hetero-difunctionalization of Alkenes. J. Am. Chem. Soc. 2018, 140, 2438. (Highlighted by X-MOL)

3. 3. Ke-Yin Ye, Hu He, Wen-Bo Liu, Li-Xin Dai, Guenter Helmchen, Shu-Li You*; Iridium-Catalyzed Allylic Vinylation and Asymmetric Allylic Amination Reactions with o-Aminostyrenes. J. Am. Chem. Soc. 2011, 133, 19006. (Highlighted by Synfacts 2012, 8, 170)

4. 4. Ke-Yin Ye, Qiang Cheng, Chun-Xiang Zhuo, Li-Xin Dai, Shu-Li You*; An Iridium(I) N-Heterocyclic Carbene Complex Catalyzes Asymmetric Intramolecular Allylic Amination Reactions. Angew. Chem., Int. Ed. 2016, 55, 8113. (Highlighted by Synfacts 2016, 12, 697)

5. 5. Ke-Yin Ye, Gerald Kehr, Constantin G. Daniliuc, Lei Liu, Stefan Grimme, Gerhard Erker*; Coupling of Carbon Monoxide with Nitrogen Monoxide at a Frustrated Lewis Pair Template. Angew. Chem., Int. Ed. 2016, 55, 9216.

6. 6. Ke-Yin Ye, Markus Bursch, Zheng-Wang Qu, Constantin G. Daniliuc, Stefan Grimme, Gerald Kehr, Gerhard Erker*; Reversible Formylborane/SO₂ Coupling at a Frustrated Lewis Pair Framework. Chem. Commun. 2017, 53, 633.

7. 7. Ke-Yin Ye, Zhidong Song, Gregory S. Sauer, Johannes H. Harenberg, Niankai Fu, Song Lin*;Synthesis of Chlorotrifluoromethylated Pyrrolidines via Electrocatalytic Radical Ene-Yne Cyclization. Chem. Eur. J. 2018, 24, 12274.

8. 8. Ke-Yin Ye, Li-Xin Dai, Shu-Li You*;Regio- and Enantioselective Synthesis of N-Allylindoles via Iridium-Catalyzed Allylic Amination/Transition-Metal-Catalyzed Cyclization Reactions. Chem. Eur. J. 2014, 20, 3040.

9. 9. Ke-Yin Ye, Xiao Zhang, Li-Xin Dai, Shu-Li You*;Ruthenium-Catalyzed Regioselective Allylic Trifluoromethylthiolation Reaction. J. Org. Chem. 2014, 79, 12106.

10. 10. Ke-Yin Ye, Constantin G. Daniliuc, Shunxi Dong, Gerald Kehr, Gerhard Erker*; Frustrated Lewis Pair Behavior of an Open, Noninteracting Phosphane/Borane Pair at a Rigid Organic Framework: Exploring Decisive Factors for FLP Activity. Organometallics. 2017, 36, 5003.

11. 11. Ke-Yin Ye, Li-Xin Dai, Shu-Li You*; Enantioselective Synthesis of 2,5-Dihydrobenzo[b]azepine Derivatives via Iridium-Catalyzed Asymmetric Allylic Amination with 2-Allylanilines and Ring-Closing-Metathesis Reaction. Org. Biomol. Chem. 2012, 10, 5932.、

12. 12. Ke-Yin Ye, Li-Xin Dai, Shu-Li You*; Synthesis of 1Z,4E,6E-Triene Derivatives by Chemo- and Regioselective Iridium-Catalyzed Dienylation of ortho-Aminostyrenes with Dienyl Carbonates. Asian. J. Org. Chem. 2013, 2, 244.

13. 13. Ke-Yin Ye, Xiaowu Wang, Constantin G. Daniliuc, Gerald Kehr, Gerhard Erker*; A Ferrocene-Based Phosphane/Borane Frustrated Lewis Pair for Asymmetric Imine Reduction. Eur. J. Inorg. Chem. 2017, 368.

14. 14. Ke-Yin Ye, Zhuo-An Zhao, Zeng-Wei Lai, Li-Xin Dai, Shu-Li You*; Highly Regioselective Allylic Substitution Reactions Catalyzed by an Air-stable (π-Allyl)iridium Complex Derived from Dinaphthocyclooctatetraene and a Phosphoramidite Ligand. Synthesis 2013, 2109.

15. 15. Ke-Yin Ye, Ke-Jia Wu, Guo-Tai Li, Li-Xin Dai, Shu-Li You*; Synthesis of Enantioenriched Indolopiperazinones via Iridium(I) N-Heterocyclic Carbene Complex Catalyzed Asymmetric Intramolecular Allylic Amination Reaction. Heterocycles2017, 95, 304. 

16. 16. Xiangyu Wu, Wei Hao, Ke-Yin Ye, Bingyang Jiang, Gisselle Pombar, Zhidong, Song, Song Lin*; Ti-Catalyzed Radical Alkylation of Secondary and Tertiary Alkyl Chlorides Using Michael Acceptors. J. Am. Chem. Soc. 2018, 140, 14836.

17. 17. Kai-Jiong Xiao, Jie-Min Luo, Ke-Yin Ye, Yu Wang, Pei-Qiang Huang*; Direct, One-Pot Sequential Reductive Alkylation of Lactams/Amides with Grignard and Organolithium Reagents through Lactam/Amide Activation. Angew. Chem., Int. Ed. 2010, 49, 3037. (Highlighted by Synfacts 2010, 7, 822)

18. 18. Qing-Feng Wu, Wen-Bo Liu, Chun-Xiang Zhuo, Zi-Qiang Rong, Ke-Yin Ye, Shu-Li You*; Iridium-Catalyzed Intramolecular Asymmetric Allylic Dearomatization of Phenols. Angew. Chem., Int. Ed. 2011, 50, 4455. (Highlighted by Synfacts 2011, 8, 854)

19. 19. Wu Li, Chao Liu, Heng Zhang, Ke-Yin Ye, Guanghui Zhang, Wangzheng Zhang, Zhengli Duan, Shu-Li You*, Aiwen Lei*; Palladium-Catalyzed Oxidative C-H/N-H Carbonylationfor the Synthesis of β-lactams. Angew. Chem., Int. Ed. 2014, 53, 2443. (Highlighted by Synfacts 2014, 10, 360)

20. 20. Hu He, Ke-Yin Ye, Qing-Feng Wu, Li-Xin Dai, Shu-Li You*; Iridium-Catalyzed Asymmetric Allylic Etherification and Ring-Closing-Metathesis Reaction for Enantioselective Synthesis of Chromene and 2,5-Dihydrobenzo[b]oxepine Derivatives. Adv. Synth. Catal. 2012, 354, 1084.

21. 21. Kai-Jiong Xiao, Yu Wang, Ke-Yin Ye, Pei-Qiang Huang*; Versatile One-Pot Reductive Alkylation of Lactams/Amides via Amide Activation: Application to the Concise Syntheses of Bioactive Alkaloids (-)-Bgugaine, (-)-Coniine, (+)-Preussin, and (-)-Cassine. Chem. Eur. J. 2012, 16, 12792.

22. 22. Thomas Őzgün, Ke-Yin Ye, Constantin G. Daniliuc, Birgit Wibbeling, Lei Liu, Stefan Grimme, Gerald Kehr, Gerhard Erker*; Why Does the Intramolecular Trimethylene-Bridged Frustrated Lewis Pair Mes₂PCH₂CH₂CH₂B(C₆F₅)₂ Not Activate Dihydrogen? Chem. Eur. J. 2016, 22, 5988.

23. 23. Zeng-Wei Lai, Rong-Fei Yang, Ke-Yin Ye, Hongbin Sun, Shu-Li You*; Synthesis of 1,1’- bis(trifluoromethyl)phosphine-oxazoline ferrocene ligands and their application in regio- and enantioselective Pd-catalyzed allylic alkylation of monosubstituted allyl substrates. Beilstein J. Org. Chem. 2014, 10, 1261.

获奖情况  

10/2018    入选福建省“闽江学者”特聘教授计划

06/2014    中国科学院三好学生

06/2012    刘铸晋优秀博士生奖学金

05/2010    中国科学院三好学生

06/2009    厦门大学优秀毕业生

其他