姓名：宋秋玲

 职称：教授，博士生导师

 学历：博士研究生

 专业：有机化学

 邮箱：qsong@fzu.edu.cn

 研究方向：有机硼化学，有机氟化学，自由基化学

 课题组主页：https://www.x-mol.com/groups/song_qiuling

工作经历：

2023.3-至今，福州大学，教授

2012.11-2023.2，华侨大学，教授

2012.1-2012.11，华侨大学，副教授

2007.1-2011.12，美国制药公司，研究员/项目主管

教育背景：

1994.09-1998.06，郑州大学，化学系，学士

1998.09-2001.06，北京大学，化学与分子工程学院，硕士（保送） (导师：席振峰 教授）

2002.09-2006.12，美国普林斯顿大学，化学系，博士 （导师：Prof. Robert A Pascal）

科研简介:

主要从事有机硼化学、有机氟化学、自由基化学方面的研究。目前已在Acc. Chem. Res.、Chem. Soc. Rev.、Nat. Chem.、Nat. Synth.、Chem、ACS. Cent. Sci.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Nat. Commun.、CCS Chem.、Sci. China Chem.等学术期刊论文发表论文一百余篇，详见课题组主页https://www.x-mol.com/groups/song_qiuling。

代表论文:

56. Copper-catalysed asymmetric hydroboration of alkenes with 1,2-benzazaborines to access chiral naphthalene isosteres, Wanlan Su, Jide Zhu, Yu Chen, Xu Zhang, Weihua Qiu, Kai Yang*, Peiyuan Yu* and Qiuling Song*, Nat. Chem. 2024, 16, 1312-1319.

55. Enantioselective construction of C-B axially chiral alkenylborons by nickel-catalyzed radical relayed reductive coupling, Weihua Qiu, Rencai Tao, Yong He, Yao Zhou, Kai Yang* and Qiuling Song*, Nat. Commun. 2024, 15, 10432.

54. Pd-Catalyzed B–H Aryl/Alkenylation of 1,2-Azaborines”, Zhen Zhang, Dandan Jiang, Peiwen Su, Kai Yang*, Peiyuan Yu, Qiuling Song*, ACS Catal. 2024, 14, 16996−17003.

53. Interception of Alkynyl Tetracoordinate Borons with Sulfur Electrophiles beyond the Zweifel Pathway, Xingxing Ma, Yuanbiao An, Luo Li, Meihui Cai, Qiuling Song*, Angew. Chem. Int. Ed. 2024, e202416579.

52. Cu-catalyzed enantioselectivee assembly of axially chiral allylic boronates, Shuai Wang, Jianbo Liu, Wenyue Ma, Qiuling Song*, Sci. China Chem., 2024, doi: 10.1007/s11426-024-2315-1.

51. Photo-induced decarboxylative C-S bond formation to access sterically hindered unsymmetric S-alkyl thiosulfonates and SS-alkyl thiosulfonates, Yu Guo, Guotao Lin, Mengjie Zhang, Jian Xu and Qiuling Song*, Nat. Commun. 2024, 15,7313.

50. Fluorinating electrophilic interception in the oxidation or protonation of alkynyl tetracoordinate borons, Xingxing Ma, Zihao Zhong, Qiuling Song*, Chem, 2024, doi: 10.1016/j.chempr.2024.07.034.

49. Copper- and Palladium-Cocatalyzed Chemo-, Regio-, Stereo-, and Atroposelective Arylboration of 1,3-Enynes, Wangyang Li, Haohua Chen, Yanping Zheng, Yong Lu, Jinhui Xie, Shanglin Chen, Yu Lan*, and Qiuling Song* ACS Catal. 2024, 14, 11318−11331.

48. Chemo-, regio- and stereoselective access to polysubstituted 1,3-dienes via Nickel-catalyzed four-component reactions, Shanglin Chen, Ya-Nan Wang, Jinhui Xie, Wangyang Li , Mingxing Ye, Xingxing Ma, Kai Yang, Shijun Li, Yu Lan* and Qiuling Song*, Nat. Commun. 2024, 15, 5479

47. Difluorocarbene-induced [1,2]- and [2,3] rearrangement of tertiary amines, Jianke Su, Yu Guo, Chengbo Li and Qiuling Song*, Nat Commun. 2024, 15, 4794.

46. Unlocking Diverse π‑Bond Enrichment Frameworks by the Synthesis and Conversion of Boronated Phenyldiethynylethylenes, Jinhui Xie, Wangyang Li, Yong Lu, Yanping Zheng, Yanying Huang, Shanglin Chen, and Qiuling Song*, J. Am. Chem. Soc. 2024, 146, 10167–10176.

45. N -Heterocycle-Editing to Access Fused-BN-Heterocycles via Ring-Opening/C-H Borylation/Reductive C-B Bond Formation, Xu Zhang, Wanlan Su, Huosheng Guo, Pengyuan Fang, Kai Yang* and Qiuling Song*, Angew. Chem. Int. Ed. 2024, 63, e202318613.

44. “Ni-catalysed assembly of axially chiral alkenes from alkynyl tetracoordinate borons via 1,3-metallate shift", Xingxing Ma, Mengwei Tan, Luo Li, Zihao Zhong, Puhui Li, Jinchao Liang and Qiuling Song * Nat. Chem. 2024, 16, 42-53.pages42–53,

43. “Palladium-Catalyzed Difluorocarbene Transfer Enabled Divergent Synthesis of γ-Butenolides and Ynones from Iodobenzene and Terminal Alkynes, Heyun Sheng, Zhiwei Chen, and Qiuling Song*, J. Am. Chem.Soc. 2024, 146, 1722–1731.

42. "Enantio- and regioselective [2 + 2 + 2] cycloaddition of BN-diynes for construction of C-B axial chirality,Hao Wang, Bolin Qiao, Jide Zhu, Huosheng Guo, Zhen Zhang, Kai Yang*, Shi-Jun Li, Yu Lan*, Qiuling Song*, Chem 2023, 10, 317–329.

41. “Palladium-Catalyzed Atroposelective Kinetic C−H Olefination and Allylation for the Synthesis of C-B Axial Chirality, Jie Xu, Weihua Qiu, Xu Zhang, Zhihan Wu, Zhen Zhang, Kai Yang, Qiuling Song*, Angew. Chem. Int. Ed. 2023, 62, e202313388

40. “Decarboxylation of β-boryl NHPI esters enables radical 1,2-boron shift for the assembly of versatile organoborons”, Yu Guo, Xiaosha Wang, Chengbo Li, Jianke Su, Jian Xu* and Qiuling Song*, Nat. Commun. 2023, 14, 5693.

39. “Transition-metal-free C(sp2)–C(sp3) cross-coupling of α-(pseudo)halo aliphatic ketones with boronic acids via a 1,4-metallate shift”, Xue Li, Haohua Chen, Hao Wang, Qiaohui Zhang, Heyun Sheng, Yu Lan* and Qiuling Song*, Nat. Synth. 2023, 2, 1211-1221.

38. “Construction of C-B axial chirality via dynamic kinetic asymmetric cross-coupling mediated by tetracoordinate boron”, Kai Yang, Yanfei Mao, Zhihan Zhang, Jie Xu, Hao Wang, Yong He, Peiyuan Yu* and Qiuling Song*, Nat. Commun. 2023, 14, 4438.

37. “Cu(I)-Catalyzed Highly Diastereo- and Enantioselective Constructions of Boron/Carbon Vicinal Stereogenic Centers via Insertion Reaction”, Guan Zhang, Xinping Cai, Junyi Jia, Bofan Feng, Kai Yang, and Qiuling Song*, ACS Catal. 2023, 13, 9502-9508.

36. “Unconventional Transformations of Difluorocarbene with Amines and Ethers”, Xingxing Ma, Jianke Su and Qiuling Song*, Acc. Chem. Res. 2023, 56, 592-607.

35. “Modular Assembly of Versatile Tetrasubstituted Alkenyl Monohalides from Alkynyl Tetracoordinate Borons”, Xingxing Ma, Luo Li, Mengwei Tan, Zihao Zhong, Jinchao Liang, Puhui Li and Qiuling Song*, Chem, 2023, doi: 10.1016/j.chempr.2023.01.005.

34. “Construction of Axially Chiral Alkenylboronates via Cu/Pd Dual Catalysis-Promoted Atroposelective Arylboration of Alkynes”, Wangyang Li, Shanglin Chen, Jinhui Xie, Zhenwei Fan, Kai Yang and Qiuling Song*, Nat. Synth. 2023, 2, 140-151.

33. “Deaminative Arylation or Alkenylation of Aliphatic Tertiary Amines with Aryl or Alkenylboronic Acids via Nitrogen Ylides”, Jianke Su, Chengbo Li, Xinyuan Hu, Yu Guo and Qiuling Song*, Angew. Chem. Int. Ed. 2022, 61, doi: 10.1002/anie.202212740.

32. “Enantioselective Copper-Catalyzed sp2/sp3 Diborylation of 1,1-Chloro-Trifluoromethyl– 2-alkenes”, Zhenwei Fan, Mingxing Ye, Yahao Wang, Jian Qiu, Wangyang Li, Xingxing Ma, Kai Yang and Qiuling Song*, ACS Cent. Sci. 2022, 8, doi: 10.1021/acscentsci.2c00339.

31. “Enantioselective Cu-catalyzed double hydroboration of alkynes to access chiral gem-diborylalkanes”, Shengnan Jin, Jinxia Li, Kang Liu, Wei-Yi Ding, Shuai Wang, Xiujuan Huang, Xue Li, Peiyuan Yu and Qiuling Song*, Nat. Commun. 2022, 13, 3524-3536.

30. “Construction of boron-stereogenic compounds via enantioselective Cu-catalyzed desymmetric B–H bond insertion reaction”,  Guan Zhang, Zhihan Zhang, Mengyuan Hou, Xinping Cai, Kai Yang, Peiyuan Yu* and Qiuling Song*, Nat. Commun. 2022, 13, 2624-2635.

29. “Photo-induced trifunctionalization of bromostyrenes via remote radical migration reactions of tetracoordinate boron species”, Chaokun Li, Shangteng Liao, Shanglin Chen, Nan Chen, Feng Zhang, Kai Yang and Qiuling Song*, Nat. Commun. 2022, 13, 1748-1760.

28. “Enantioselective Cobalt-Catalyzed Cascade Hydrosilylation and Hydroboration of Alkynes to Access Enantioenriched 1,1-Silylboryl Alkanes”, Shengnan Jin, Kang Liu, Shuai Wang, and Qiuling Song*, J. Am. Chem. Soc. 2021, 143, 13124-13134.

27. “Difluorocarbene enables to access 2-fluoroindoles from ortho-vinylanilines”, Jianke Su, Xinyuan Hu, Hua Huang, Yu Guo and Qiuling Song*, Nat. Commun. 2021, 12, 4986-4996.

26. “Construction of Axially Chiral Arylborons via Atroposelective Miyaura Borylation”, Kai Yang, Yanfei Mao, Jie Xu, Hao Wang, Yong He, Wangyang Li and Qiuling Song*, J. Am. Chem. Soc. 2021, 143, 10048–10053.

25. “Tetracoordinate Boron Intermediates Enabled Unconventional Transformations”, Kai Yang and Qiuling Song*, Acc. Chem. Res.,2021, 54, 2298–2312.

24. “Elemental sulfur enabled divergent synthesis of disulfides, diselenides and polythiophenes from β-CF3-1,3-enynes”, Shengnan Jin, Shi-Jun L, Xingxing Ma, Jianke Su, Haohua Chen, Yu Lan* and Qiuling Song*, Angew. Chem. Int. Ed. 2021, 60, 881-888.

23. “Recent Progress on Selective Deconstructive Modes of Halodifluoromethyl and Trifluoromethyl-containing Reagents”, Xingxing Ma and Qiuling Song*, Chem. Soc. Rev., 2020, 49, 9197-9219.

22. “Cu-catalyzed regio- and stereodivergent chemoselective sp2/sp3 1,3-and 1,4-diborylations of CF3-containing 1,3-enynes”, Zhijie Kuang, Haohua Chen, Jian Qiu, Zongliang Ou, Yu Lan* and Qiuling Song*, Chem, 2020, 6, 2347-2363.

21. “Deconstructive Functionalizations of Unstrained Carbon−Nitrogen Cleavage Enabled by Difluorocarbene”, Jianke Su, Xingxing Ma, Zongliang Ou, Qiuling Song*, ACS Cent. Sci. 2020, 6, 1819-1826.

20. “Passerini-Type Reaction of Boronic Acids Enables α-Hydroxyketones”, Kai Yang, Feng Zhang, Tongchang Fang, Chaokun Li, Wangyang Li, and Qiuling Song*, Nat. Commun. 2020, 12, 441-450.

19. “Design, Synthesis, and Applications of ortho-Sulfur Substituted Arylphosphanes”, Yu Guo, Ying Luo, Shiqiang Mu, Jianke Su, Jian Xu and Qiuling Song*, CCS Chem. 2022, DOI:10.31635/ccschem.022.202201944.

18. “Deconstructive Difunctionalizations of Carbon-Oxygen Cleavage in Cyclic Ethers Enabled by Difluorocarbene to Access Difluoromethyl Ethers”, Heyun Sheng, Jianke Su, Xue Li and Qiuling Song*, CCS Chem. 2022, DOI: 10.31635/ccschem.022.202101576.

17. “Atom Recombination of Difluorocarbene Enables 3-Fluorinated Oxindoles from 2-Aminoarylketones”. Guan Zhang , Qianqian Shi , Mengyuan Hou , Kai Yang , Shihui Wang , Shuai Wang , Wangyang Li , Chaokun Li , Jian Qiu , Hetao Xu , Lu Zhou , Cece Wang , Shi-Jun Li , Yu Lan* , and Qiuling Song*, CCS Chemistry. 2021, 3, 1613–1621.

16. “Catalytic Atroposelective Catellani Reaction Enables to Construct Axially Chiral Biaryl Monophosphine Oxides”, Qiang Feng, Xingxing Ma, Wen Bao, Shi-Jun Li, Yu Lan*, and Qiuling Song*, CCS Chemistry. 2021, 3, 377-387.

15. “Palladium-catalyzed Three-component Synthesis of Phosphine-containing Tetrasubstituted Acyclic Unsymmetric Allcarbon Olefins”, Xingxing Ma, Puhui Li, Jinchao Liang, Hejun An, Kai Yang, and Qiuling Song *, Cell Rep. Phy. Sci. 2020, 2, 100629-100641.

14. “Transition-Metal-Free Double Insertive Coupling of Isocyanides with Arylboronic Acids Enabled Diarylmethanamines”, Kai Yang, Xiaoxiao Hu, Wangyang Li, Jian Qiu, Qiang Feng, Shihui Wang, Guan Zhang, Zhijie Kuang, Peiyuan Yu* and Qiuling Song*, Cell Rep. Phy. Sci. 2020, 1, 100268-100283.

13. “Palladium-catalyzed Suzuki-Miyaura coupling of thioureas or thioamides”, Shaoyu Mai, Wendong Li, Xue Li, Yingwei Zhao, Qiuling Song*, Nat. Commun. 2019, 10, 5709-5731.

12. “Michael Reaction Inspired Atroposelective Construction of Axially Chiral Biaryls”, Shengyi Yan, Wang Xia, Shaoyu Li, Qiuling Song*, Shaohua Xiang, Bin Tan*, J. Am. Chem. Soc. 2020, 142, 7322-7327.

11. “Chiral Brønsted Acid from Chiral Phosphoric Acid Boron Complex and Water: Asymmetric Reduction of Indoles” Kai Yang, Yixian Lou, Chenglan Wang, Liang-Wen Qi, Tongchang Fang, Feng Zhang, Hetao Xu, Lu Zhou, Wangyang Li, Guan Zhang, Peiyuan, Yu*, Qiuling Song*, Angew. Chem. Int. Ed. 2020, 59, 3294-3299.

10. “Stereospecific 1,4-Metallate Shift Enables Stereoconvergent Synthesis of Ketoximes”, Kai Yang, Feng Zhang, Tongchang Fang, Guan Zhang, Qiuling Song*, Angew. Chem. Int. Ed.  2019, 58, 13421-13426.

9. “Divergent Synthesis of Disulfanes and Benzenesulfonothioates Bearing 2-Aminofurans From N-Tosylhydrazone-Bearing Thiocarbamates”, Shaoyu Mai and Qiuling Song*, Angew. Chem. Int. Ed. 2017, 56, 7952-7957.

8. “Radical-Induced 1,2-Boron Shift, Enabling 1,3-Difunctionalization of Allylboronic Esters”, Kai Yang,  Zhijie Kuang, Qiuling Song*, Chem  2020, 6, 330-331.

7. “Design and Applications of Highly Stereoselective 1, 3-Dienes Aldehydes or Ketones”, Qiang Feng, Shihui Wang, Xingxing Ma, Changqing Rao and Qiuling Song*, Sci. China. Chem. 2022, doi:10.1007/s11426-021-1204-5.

6. “C-F bond activation under transition-metal-free conditions”, Han-Jun Ai, Xingxing Ma, Qiuling Song and Xiao-Feng Wu*, Sci. China Chem. 2021, 64, 1630-1659.

5. “Base-catalyzed Diborylation of Alkynes: Synthesis and Applications of cis-1,2-Bis(boryl)alkenes”, Zhijie Kuang, Guoliang Gao and Qiuling Song*, Sci. China Chem. 2020, 62, 62-66.

4. “Base-Catalyzed Highly Diastereoselective Deuteration of Diarylethynes via Domino-Borylation-Protodeboronation”, Zhijie Kuang, Shaoyu Mai, Kai Yang and Qiuling Song*, Sci. Bull., 2019, 22, 1685-1690.

3. “Enantio- and Diastereoselective Diarylmethylation of 1,3-Dicarbonyl Compounds”, Xin Li, Songtao He and Qiuling Song*, Chem. Sci. 2020, 11, 5969-5973.

2. “S8-Catalyzed Triple Cleavage of Bromodifluoro Compounds for the Assembly of N-containing Heterocycles”, Shuilin Deng, Haohua Chen, Xingxing Ma, Yao Zhou, Kai Yang, Yu Lan*, and Qiuling Song*, Chem. Sci. 2019, 10, 6828-6833.

1. “Four-Coordinate Triarylborane Synthesis via Cascade B-Cl/C-B Cross-Metathesis and C-H Bond Borylation”, Kai Yang, Guan Zhang and Qiuling Song*, Chem. Sci. 2018, 9,7666-7672.

获奖情况：

曾入选福建百人计划；荣获2015年福建省五四青年奖章、2016年度第六届中国侨界贡献奖（创新人才）、2018 ACP Lectureship Awards (Singapore and Japan)、2019 ACP Lectureship Awards (Taiwan and Korea) 、2021年Thieme Chemistry Journal Awards（2021），以及药明康德生命化学研究奖（2022）等；2021年当选英国皇家化学学会会士。

社会兼职：

目前担任Organic letters 的编委、Journal of Heterocyclic Chemistry和Green Synthesis & Catalysis的副主编，担任《中国化学快报》(Chinese Chemical Letters)、《化学学报》和《中国医药工业杂志》的编委，以及《有机化学》(Chinese Journal of Organic Chemistry)青年编委。

其他：

诚招硕士研究生、博士研究生、研究助理、博士后。